Ethylene chloride, also known as 1,2-dichloroethane, is a chemical compound primarily used as an industrial solvent and in the production of various chemicals. It has limited medicinal uses and is primarily employed in industrial applications. Here’s some information on the preparation, test for purity, assay, and limited medicinal uses of ethylene chloride:

Preparation of Ethylene Chloride:

Ethylene chloride is typically prepared by the reaction of ethylene gas with chlorine gas in the presence of a catalyst, such as ferric chloride or cupric chloride. The reaction produces ethylene chloride as the main product.

Test for Purity of Ethylene Chloride:

Several tests can be conducted to assess the purity of ethylene chloride, including the following:

  1. Gas chromatography: Gas chromatography can be used to analyze the composition of the ethylene chloride sample and identify the presence of any impurities.
  2. Distillation: Distillation can be employed to separate ethylene chloride from impurities or other compounds that may be present in the sample.

Assay of Ethylene Chloride:

An assay is performed to determine the concentration or purity of ethylene chloride in a given sample. The assay method for ethylene chloride generally involves titration or gas chromatography to quantify the amount of ethylene chloride present.

Medicinal Uses of Ethylene Chloride:

Ethylene chloride has limited medicinal uses, mainly as a topical agent for the treatment of localized skin infections caused by certain fungi. However, due to its toxic nature and potential health risks, its medical applications are limited, and safer alternatives are typically preferred.

It’s important to note that the use of ethylene chloride in medicinal applications is not common in modern medical practice, and it is primarily utilized in industrial settings as a solvent, degreaser, or intermediate chemical in the production of various compounds.

PATH: PHARMD/PHARMD NOTES/ PHARMD FIRST YEAR NOTES/ ORGANIC CHEMISTRY/ PHARMACEUTICAL ORGANIC CHEMISTRY/ ETHYL CHLORIDE (OR) ETHYLENE CHLORIDE.

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